Nicole Dinaut

Nicole Dinaut is a Registered Patent Agent with the Canadian Intellectual Property Office and with the United States Patent and Trademark Office. She practises in the Intellectual Property Department in the Toronto office, specializing in biotechnological, pharmaceutical and chemical matters. 

Nicole has experience in drafting and prosecution of patent applications, and advising clients with respect to the strategic development and management of their patent portfolios.  Nicole also provides technical support for pharmaceutical patent litigation.

Prior to joining Osler, Nicole worked at another leading, international law firm.  Before entering the legal field, she carried out postdoctoral research at the Massachusetts Institute of Technology.  Nicole has extensive interdisciplinary research experience encompassing areas such as synthetic organic chemistry, enzyme kinetics, immunology, molecular biology, and drug design and development.

Latest Insights

  • Osler Update May 4, 2022

    Act now: Request examination early to avoid excess claims fees and other restrictions under proposed new Canadian Patent Rules

    The Government of Canada is proposing amendments to the Canadian Patent Rules that will introduce excess claims fees and a Request for Continued...

    Read more
    Act now:  Request examination early to avoid excess claims fees and other restrictions under proposed new Canadian Patent Rules
  • Osler Update Oct 29, 2019

    Change is coming with new Canadian Patent Rules/amended Patent Act

    New Canadian Patent Rules (Rules) and amendments to the Canadian Patent Act (the Act) will come into force on October 30, 2019. This Update...

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  • Osler Update Jun 24, 2016

    Privilege for patent and trademark agents now in force in Canada

    This new statutory privilege represents a significant improvement to Canada's intellectual property regime. Learn more.

    Read more

Speaking and Writing

Published Work

Selected Professional Presentations

  • "Careers for Chemists – Patent Agency" – Nontraditional Careers for Chemists Workshop, Department of Chemistry, University of Toronto (December 12, 2011).
  • Life Sciences Career Day, University of Toronto (June 17, 2011).
  • Tutor at MaRS Best Practices Series:  Drafting a Patent Application (2008, 2010).
  • Speaker at MaRS Life Sciences Series:  IP Strategies for Therapeutics (March 20, 2008). 

    Selected Scientific Presentations and Publications

    • Marquis J.C., Hillier S.M., Dinaut A.N., Rodrigues, D., Mitra K., Essigmann J.M., Croy R.G. Disruption of gene expression and induction of apoptosis in prostate cancer cells by a DNA-damaging agent tethered to an androgen receptor ligand.  Chemistry & Biology, 12(7): 779-87, 2005.
    • Sharma, U., Marquis, J.C., Dinaut, A.N., Hillier, S.M., Fedeles, B., Rye, P.T., Essigmann, J.M. and Croy, R.G.  Design, synthesis, and evaluation of estradiol-linked genotoxicants as anti-cancer agents.  Bioorganic & Medicinal Chemistry Letters, 14:  3829-3833, 2004.
    • Dinaut, A. N., Marquis, J. C., Rodrigues, D. C., Hillier, S.,  Rye, P. T., Zayas, B., Essigmann, J. M., Croy, R. G.,“A New Bifunctional Compound that Rapidly Induces Cell Cycle Arrest and Apoptosis in LNCaP Prostate Cancer Cells and Inhibits Growth of Prostate Cancer Xenografts”, American Association for Cancer Research, July 2003, Washington, D.C. (poster).
    • Jia, Z.C., Ye, Q.L., Dinaut, A.N., Wang, Q.P., Waddleton, D., Payette, P., Ramachandran, C., Kennedy, B., Hum, G., and Taylor, S.D. Structure of protein tyrosine phosphatase 1B in complex with inhibitors bearing two phosphotyrosine mimetics.  Journal of Medicinal Chemistry, 44: 4584-4594, 2001.
    • Dinaut, A.N. and Taylor, S.D. Antibody-catalyzed activation of a model tripartate prodrug by a tandem hydrolysis-1,6-elimination reaction.  Chemical Communications, 1386-1387, 2001.
    • Dinaut, A.N., Chen, M.J., Marks, A., Batey, R.A., and Taylor, S.D. Hydrolysis of an N-methylcarbamate by a catalytic antibody.  Chemical Communications, 385-386, 2000.
    • Taylor, S.D., Kotoris, C.C., Dinaut, A.N., Wang, Q.P., Ramachandran, C., and Huang, Z. Potent non-peptidyl inhibitors of protein tyrosine phosphatase 1B.  Bioorganic & Medicinal Chemistry, 6: 1457-1468, 1998.



  • University of Toronto, Ph.D. (Biological/Organic Chemistry)
  • St. Francis Xavier University, B.Sc. (Honours Chemistry)


  • English

Professional Affiliations

  • Intellectual Property Institute of Canada
  • Association of University Technology Managers
  • Toronto Intellectual Property Group
  • Canadian Society for Chemistry